Product Introduction
Berberine Hydrochloride (Berberine HCl) is a natural isoquinoline alkaloid extracted from traditional medicinal plants. It is widely used as a premium botanical ingredient in dietary supplements, nutraceuticals, functional foods, herbal formulations, and pharmaceutical-related applications.
Our Berberine Hydrochloride powder is manufactured using advanced extraction and purification technology to ensure high purity, stable quality, and batch-to-batch consistency.
Available specifications include: Berberine HCl 97% / 98%
Product Name
Berberine Hydrochloride Powder
Other Names
- Berberine HCl
- Berberine Hydrochloride Extract
- Berberine Hydrochloride Powder
- Berberine Chloride Hydrochloride
- Huanglian Extract
- Coptis Chinensis Extract
Latin Name
Coptis chinensis Franch.
(Chinese Goldthread)
Other botanical sources:
- Phellodendron amurense Rupr.
- Berberis aristata DC.
- Berberis vulgaris L.

Certificate of Analysis
CERTIFICATE OF ANALYSIS
| Product Name: Berberine HCl | Plant Part Used: Bark |
| Botanical Name: Coptis chinensis Franch. |
Quantity: 500kgs |
| ITEM |
SPECIFICATION | RESULTS |
| Physical&Chemical Control | ||
| Appearance | Fine powder | Complies |
| Color | Yellow | Complies |
| Odor&Taste | Characteristic | Complies |
| Loss On Drying | ≤12% | 11.09% |
| Ash | ≤0.2% | 0.16% |
| Assay (Berberine HCl;HPLC) | ≥97% | 98.42% |
| Sieve Analysis | 95% pass 80 mesh | Complies |
| Heavy Metals | ≤10ppm | Complies |
| Cadmium(Cd) | ≤1ppm | Complies |
| Mercury(Hg) | ≤0.1ppm | Complies |
| Arsenic(As) | ≤2ppm | Complies |
| Lead(Pb) | ≤3ppm | Complies |
| Pesticide residues | CP2015 | Complies |
| Microbiological Control | ||
| Total plate count | ≤1000 CFU/g | Complies |
| Yeast & mold | ≤100 CFU /g | Complies |
| E.coli | Negative | Negative |
| Salmonella | Negative | Negative |
Conclusion: Conform with specification
Storage: Stored in dry and cool place, keep away from strong light and heat.
Shelf Life: Two years when stored properly
Functions and Usages
Berberine Hydrochloride (Berberine HCl) is a naturally occurring isoquinoline alkaloid extracted from traditional medicinal plants such as Coptis chinensis (Chinese Goldthread), Berberis species, and Phellodendron species.
As a premium botanical active ingredient, Berberine HCl is widely used in dietary supplements, nutraceutical products, functional foods, and herbal formulations due to its multiple biological activities, including metabolic support, antioxidant properties, digestive health support, and cardiovascular wellness applications.
Key Benefits of Berberine Hydrochloride
1. Metabolic Health Support
Berberine Hydrochloride is one of the most researched natural plant compounds for metabolic wellness.
It supports:
- Healthy glucose metabolism
- Normal insulin sensitivity
- Balanced energy metabolism
- Healthy carbohydrate utilization
Berberine activates important metabolic pathways, including AMP-activated protein kinase (AMPK), which plays a key role in cellular energy regulation.
Application:
- Blood sugar support supplements
- Metabolic health formulas
- Weight management products
- Nutritional supplements
2. Blood Sugar Management Support
Berberine HCl is commonly used in natural health products designed to support healthy blood glucose levels.
Potential functions include:
- Supporting normal glucose metabolism
- Helping maintain healthy insulin response
- Supporting carbohydrate metabolism
Popular Product Forms:
- Berberine capsules
- Berberine tablets
- Combination formulas with chromium, cinnamon extract, alpha lipoic acid, etc.
3. Cardiovascular Health Support
Berberine Hydrochloride is widely researched for cardiovascular wellness applications.
It may help support:
- Healthy cholesterol metabolism
- Normal lipid balance
- Healthy circulation
- Cardiovascular function
Applications:
- Heart health supplements
- Cholesterol support formulas
- Herbal wellness products
OEM & ODM Service
WEHENGFOOD offers a one-stop OEM & ODM service for berberine hydrochloride production, processing, and packaging customization, including tablets, powders, granules, hard capsules, soft capsules, gummies, etc., tailored to specific customer needs.

Factory
1. Raw Material Selection & Inspection
Selection of high-quality botanical raw materials
- Identification of plant species
- Supplier qualification assessment
- Quality inspection of raw materials
- Testing for pesticides, heavy metals, microorganisms, and contaminants
2. Cleaning & Pre-processing
Preparation of raw materials before extraction
- Washing and impurity removal
- Drying and moisture control
- Cutting, crushing, and milling
- Preparation of uniform botanical powder
3. Extraction
Extraction of active ingredients from plants
- Solvent extraction (water, ethanol, etc.)
- Ultrasonic extraction / reflux extraction
- Optimization of temperature, time, and solvent ratio
- Transfer of bioactive compounds into extract solution
4. Filtration & Separation
Removal of insoluble materials and impurities
- Coarse filtration
- Fine filtration
- Centrifugation and purification
- Obtaining clear extract liquid
5. Concentration
Increasing the concentration of active compounds
- Vacuum evaporation
- Low-temperature concentration technology
- Removal of excess solvent
- Improvement of extract potency
6. Purification & Refinement
Enhancing purity and quality of the extract
- Resin purification
- Membrane filtration
- Removal of unwanted components
- Standardization of active ingredients
7. Drying
Conversion of liquid extract into powder form
- Spray drying
- Freeze drying (for heat-sensitive ingredients)
- Moisture control
- Production of stable botanical extract powder
8. Milling & Sieving
Improving powder quality and consistency
- Fine grinding
- Particle size control
- Uniform powder appearance
9. Blending & Standardization
Ensuring consistent product specifications
- Adjustment of active ingredient content
- Mixing with carriers if required
- Batch consistency control
10. Quality Control Testing
Comprehensive quality assurance
- HPLC / GC analysis
- Active compound identification
- Microbial testing
- Heavy metal testing
- Residual solvent testing
- Stability testing
11. Packaging
Professional packaging solutions
- Aluminum foil bags
- Drums
- Customized OEM packaging
- Labeling and batch coding
12. Storage & Shipment
Safe delivery to global customers
- Temperature and humidity-controlled storage
- Documentation preparation
- International logistics support
- Global export service

Package

Exhibitions

FAQ
What are the main benefits of Berberine Hydrochloride?
Berberine Hydrochloride is commonly used to support metabolic health, glucose metabolism, cardiovascular wellness, digestive health, antioxidant protection, and healthy aging.
What is Berberine HCl used for?
Berberine HCl is mainly used in dietary supplements, nutraceutical products, functional foods, and herbal formulations.
Why is Berberine Hydrochloride popular in supplements?
Berberine HCl is popular because it is a natural botanical compound with extensive research background and broad applications in metabolic and wellness products.
What supplement forms can be made with Berberine HCl?
Manufacturers can produce:
- Capsules
- Tablets
- Softgels
- Gummies
- Powder sachets
- Customized formulas











